Thesis Diary

This blog is a form of digital diary for my second year thesis development process at the
Master of Fine Arts - Design and Technology (MFADT) program at Parsons School of Design

Monday, August 02, 2004

Gene Networks

Gene Disruption Networks - Biological meaning of neighbourhoods

Example
Copyright European Bioinformatics Institute. For a larger version of this image click here.

Neighbourhood of mating response genes. 20 genes in mating response (in red) were selected, and their immediate neighbours in the network work analysed. Many neighbouring genes are related. For more information click here.


Gene Regulatory Network

Example
Copyright Dr. Martin Stetter

A network structure that represents the dependences between the different genes. "We could think that important nodes (genes) are the ones that have more connections, but it turns out that the most important ones are the ones that have more load." For more information click here.


Computational Biology - Soft Clustering

Example
Copyright Computational Group. For a larger version of this image click here.

A soft clustering of genes in a subset of the compendium data set for S. cerevisiae of Hughes et.al. 1999. The lines connect genes or experiments that exhibit strong correlations (red more so than black lines). The placement of the points in the plane is chosen to put correlated points close to each other. The coloring of the points expresses their correlation to the selected point (red in the large cluster). For more information click here.

1 Comments:

At 6:09 PM, Chris said...

Manuel - Awesome blog. I just checked it out. I've been looking into self-organizing systems a bit. I picked up this book recently:
Self-Organization in Biological SystemsIt's science oriented of course, but not too complex to learn from.

 

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